The chromosomal defect associated with Down Syndrome is trisomy 21, which results in an extra copy of chromosome 21 in somatic cells, resulting in a total of 47 chromosomes.
Down Syndrome is a genetic disorder caused by a chromosomal defect known as trisomy 21. This means there is an extra copy of chromosome 21 in somatic cells, resulting in a total of 47 chromosomes instead of the usual 46.
This is the cause of the physical and cognitive disabilities associated with Down Syndrome, as well as the characteristic facial features that are often present. It is the most common genetic cause of intellectual disability, and is estimated to affect 1 in every 700 babies born around the world.
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